Monk fruit, also known as luo han guo, is a round green melon native to central Asia. It has been used in traditional Chinese medicine for at least hundreds of years, with applications including treatment of diabetes and respiratory illnesses.

Monk fruit sweetener, especially concentrated extracts, are notably high in the mentioned mogrosides triterpenes which have been shown to exhibit strong antioxidant, anti-inflammatory, anticancer and blood glucose controlling activity.

Luo han guo extracts and lakanto sugars are significant natural sugar substitutes for diabetics or those on a low calorie diet. Monk fruit sweeteners are often compared to stevia, another no calorie sweetener commonly recommended to diabetics because it does not raise blood sugar levels.